Higher Antioxidant Levels Linked to Lower Dementia Risk

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SUMMARY: People with higher levels of the s lutein, zeaxanthin, and beta-cryptoxanthin may have a lower risk of dementia, researchers report.
People with higher blood levels of antioxidants are less likely to develop dementia, according to a study published in the journal Neurology.
People with the highest blood levels of the antioxidants lutein, zeaxanthin and beta-cryptoxanthin were less likely to develop dementia decades later than those with lower levels of antioxidants, the study found.

Lutein and zeaxanthin are found in leafy green vegetables such as kale, spinach, broccoli, and peas.Beta-cryptoxanthin is found in fruits such as oranges, papayas, tangerines, and persimmons.
“Expanding people’s cognitive function is an important public health challenge,” said study author May A. Beydoun, Ph.D., MPH, from the National Institute on Aging at the National Institutes of Health in Baltimore, Maryland.
Antioxidants may help protect the brain from oxidative stress that can lead to cell damage. Further research is needed to test whether adding these antioxidants helps protect the brain from dementia.”
The study involved 7,283 people who were at least 45 years old at the start of the study.At the start of the study, they had physical exams, interviews and blood tests to find out about antioxidant levels.They were then followed for an average of 16 years to see who developed dementia.
Participants were divided into three groups based on levels of antioxidants in their blood.People with the highest levels of lutein and zeaxanthin were less likely to develop dementia than those with lower levels of lutein and zeaxanthin.
For each standard deviation increase in lutein and zeaxanthin levels, approximately 15.4 micromoles per liter, the risk of dementia was reduced by 7%.For beta-cryptoxanthin, each standard deviation increase in levels (approximately 8.6 micromoles per liter) was associated with a 14% lower risk of dementia.
“It is important to note that these antioxidants have a reduced effect on dementia risk when we take into account other factors such as education, income and physical activity, so these factors may help explain antioxidant levels and dementia.” Baden said.
One limitation of the study is that antioxidant levels are based on one measurement of blood levels and may not reflect levels in people’s lifetimes.

Post time: May-31-2022